JBrowse

JBrowse 2 is a high-performance, pluggable genome browser designed to visualize complex structural variants and comparative genomics through a modular React-based architecture.

JBrowse 2 expands genomic visualization beyond the standard linear track: it integrates circular views, dotplots, and synteny maps into a single interface. The platform leverages React and TypeScript to process large-scale files (including VCF, BAM, and CRAM formats) directly in the browser. It supports advanced comparative analysis (such as aligning the GRCh38 human reference against CHM13) and utilizes a robust plugin system for custom data rendering. This tool provides the speed and flexibility required for modern bioinformatics pipelines and large-scale sequencing projects.

https://jbrowse.org/jb2/